List of publications until 2009

For a list of publications and some full text articles click on  TARGIT publications and results website

BENEFICIAL EFFECTS OF INTRAOPERATIVE RADIOTHERAPY ON TUMOR MICROENVIRONMENT COULD IMPROVE OUTCOMES JAYANT S. VAIDYA GUSTAVO BALDASSARRE SAMUELE MASSARUT. Int. J. Radiation Oncology Biol. Phys., Vol. 74, No. 3,  976, 2009.

Targeted Intraoperative Radiotherapy Impairs the Stimulation of Breast Cancer Cell Proliferation and Invasion Caused by Surgical Wounding Barbara Belletti, Jayant S. Vaidya, Sara D'AndreaFrank Entschladen,Mario Roncadin, Francesca Lovat, Stefania Berton, Tiziana Perin,Ezio CandianiSonia Reccanello, Andrea VeronesiVincenzo Canzonieri,Mauro G. TrovòKurt S. ZaenkerAlfonso ColombattiGustavo Baldassarre and Samuele Massarut. Clinical Cancer Research Vol 14 (5): 1 Mar 2008

Sphere of equivalence - a novel target volume concept for Intraoperative Radiotherapy using low-energy X-Rays. Herskind C, Griebel J, Kraus-Tiefenbacher U, Wenz F: Int. J. Radiation Oncology Biol. Phys., Vol. 72, No. 5, pp. 1575 - 1581, 2008.

Early initiation of external beam radiotherapy (EBRT) may increase the risk of long-term toxicity in patients undergoing intraoperative radiotherapy (IORT) as a boost for breast cancer.Wenz F., Welzel G., Keller A., Blank E., Vorodi F., Herskind C., Tomé O., Sütterlin M., Kraus-Tiefenbacher U: The Breast , Volume 17, Issue 6, Pages 617 - 622

Breast Seroma after Intraoperative Radiotherapy with low kV X-Rays.Kraus-Tiefenbacher U, Hermann B, Siebenlist T, Keller A, Steil V, Herskind C, Tome O, Sütterlin M, Wenz F: Rev. Cancer 2008; 22, No Extra:22

Efficacy of Targeted Intraoperative Radiotherapy (TARGIT) boost after breast conserving surgery: Updated results.Vaidya JS, Baum M, Tobias JS, Massarut S, Wenz F, Hilaris B, C, Corica T, Roncadin M, Keshtgar M, Kraus-Tiefenbacher U, Saunders C, Joseph D: J Clin Oncol 2008;26:565.

The influence of the interval between IORT during breast-conserving surgery and external beam radiotherapy (EBRT) on late toxicity.Welzel G, Blank E, Kraus-Tiefenbacher U, Keller A, Vorodi F, Herskind C, Tomé O, Sütterlin M, Wenz FK: J Clin Oncol 2008;26:630.

Breast Seroma after Intraoperative Radiotherapy with low kV X-Rays.Kraus-Tiefenbacher U, Hermann B, Siebenlist T, Keller A, Steil V, Herskind C, Tome O, Sütterlin M, Wenz F: Rev. Cancer 2008; 22, No Extra:22

Breast cancer patients treated with intra-operative radiotherapy [IORT] alone when conventional external beam radiation therapy [EBRT] was not possible.Keshtgar M, Tobias JS, Vaidya JS, Williams N, Stacey C, Metaxas M, Douek M, Brew-Graves C, Baum M J Clin Oncol 2008;26:11517.

Die intraoperative Strahlentherapie (IORT) ist eine Option für Patientinnen mit lokal rezidiviertem Mammakarzinom nach vorheriger externer Strahlentherapie.Vorodi F, Kraus-Tiefenbacher U, Bauer L, Tome O, Steil V, Wenz F: J Onkologie 2008;3:29-34.

Early initiation of external beam radiotherapy (EBRT) increases the risk of long term toxicity in patients undergoing intraoperative radiotherapy (IORT) as a boost for breast cancer.Blank E, Welzel G, Keller A, Vorodi F, Herskind C, Scheda A, Tomé O, Sütterlin M, Kraus-Tiefenbacher U, Wenz F: Onkologie 2008;31(suppl. 1):1-221 (Abstract).

Intraoperative radiotherapy (IORT) is an option for patients with localized breast recurrences after previous external-beam radiotherapy.Kraus-Tiefenbacher U, Bauer L, Scheda A, Schoeber C, Schaefer J, Steil V, Wenz F: BMC Cancer 2007; 7:178.

Early mammographic and sonographic findings after intraoperative radiotherapy (IORT) as a boost in patients with breast cancer.Wasser K, Schoeber C, Kraus-Tiefenbacher U, Bauer L, Brade J, Teubner J, Wenz F, Neff W: Eur Radiol 2007;17:1865-74.

Measurement of Skin Dose from Very Low Energy X-rays during Partial Breast Irradiation.Armoogum K, Parry J, Mackay C, Thompson A, Vaidya J, Ackland C, Gardner J, Munro A: Clin Oncol (R Coll Radiol) 2007;19(3 Suppl):S23.

Partial breast irradiation using targeted intraoperative radiotherapy (Targit).Vaidya JS: Nature Clin Practice Oncol 2007;4:384-5.

Intraoperative radiotherapy (IORT) with low-energy x-rays for breast cancer.Kraus-Tiefenbacher US, Herskind C, Bauer L, Scheda A, Wenz F: J Clin Oncol 2007;25:607.

Sphere of equivalence for tumour-bed recurrence after intraoperative radiotherapy with low-energy X-rays compared with external beam radiotherapy.Herskind C, Kraus-Tiefenbacher U, Wenz F: The Breast 2007;16:S37.

Long-term toxicity of an intraoperative radiotherapy (IORT) boost using low energy X-rays during breast conserving surgery (BCS). Kraus-Tiefenbacher U, Bauer L, Scheda A, Fleckenstein K, Keller A, Herskind C, Steil V, Melchert F, Wenz F: The Breast 2007;16:S39.

Intraoperative Radiotherapie (IORT) beim Mammakarzinom mit dem INTRABEAM-System. Wenz F, Steil V, Herskind C, Sommer H, Friese K, Sütterlin M, Kraus-Tiefenbacher U: Der Gynäkologe 2007;6:463-5.

Long-term toxicity of an intraoperative radiotherapy boost using low-energy X-rays during breast-conserving surgery.Kraus-Tiefenbacher U, Bauer L, Scheda A, Fleckenstein K, Keller A, Herskind C, Steil V, Melchert F, Wenz F: Int J Rad Oncol. Biol Phys 2006;66:377-81.

Targeted intraoperative radiotherapy (TARGIT) yields very low recurrence rates when given as a boost.
Vaidya J, Baum M, Tobias J, Massarut S, Wenz F, Murphy O, Hilaris B, Houghton J, Saunders C, Corica T, Roncadin M, Kraus-Tiefenbacher U, Melchaert F, Keshtgar M, Sainsbury R, Douek M, Harrison E, Thompson A, Joseph D.
Int J Radiat Oncol Biol Phys 2006;66(5):1335-1338

Breast-conserving surgery with intra-operative radiotherapy: the right approach for the 21st century?
Tobias JS, Vaidya J, Keshtgar M, Douek M, Metaxas M, Stacey C, Sainsbury R, D?Souza D, Baum M.
Clin Oncol 2006;18: 220-228

Long-term toxicity of an intraoperative radiotherapy boost using low energy X-rays during breast-conserving surgery.
Kraus-Tiefenbacher U, Bauer L, Scheda A, Fleckenstein K, Keller A, Herskind C, Steil V, Melchert F, Wenz F.
Int J Radiat Oncol Biol Phys 2006;66(2):377-81


In favour of partial breast irradiation in selected patients and a well-directed intraoperative boost.
Vaidya J.
Breast 2006;15(5):581-3

Intraoperative radiotherapy impairs breast cancer cell motility induced by surgical wound fluid.
Massarut S, Baldassarre G, Belletti B, Colombatti, D'Andrea A, Ezio C, Perin T, Reccanello S, Roncadin M, Vaidya J.
Journal of Clinical Oncology, 2006 ASCO Annual Meeting Proceedings Part I. Vol 24, No. 18S (June 20 Supplement), 2006: 1061

Single dose targeted intraoperative radiotherapy (TARGIT) for breast cancer can be delivered as a second procedure under local anaesthetic.
Vaidya J, Walton L, Dewar J.
World J Surg Oncol 2006;4:2

Mathematical modelling of radiotherapy strategies for early breast cancer.
Enderling H, Anderson A, Chaplain M, Munro A, Vaidya J.
J Theor Biol 2006;241(1):158-71

Intraoperative radiotherapy (IORT) for breast cancer using the Intrabeam system.

Kraus-Tiefenbacher U, Scheda A, Steil V, Hermann B, Kehrer T, Bauer L, Melchert F, Wenz F.
Tumori 2005;91: 339-345
 
Targeted intraoperative radiotherapy (TARGIT): an innovative approach to partial-breast irradiation.
Vaidya J, Tobias J, Baum M, Wenz F, Kraus-Tiefenbacher U, D'Souza D, Keshtgar M, Massarut S, Hilaris B, Saunders C, Joseph D.
Semin Radiat Oncol 2005;15(2):84-91
 
Radiobiological aspects of intraoperative radiotherapy (IORT) with isotropic low-energy X rays for early-stage breast cancer.
Herskind C, Steil V, Kraus-Tiefenbacher U, Wenz F.
Radiation Research 2005;2:208-215

Prospective trials of intraoperative radiation treatment for breast cancer.
Joseph D, Bydder S, Jackson LR, Corica T, Hastrich D, Oliver D, Minchin D, Haworth A, Saunders C.
ANZ J. Surg. 2004;74 1043?1048
 
Intraoperative radiotherapy: the debate continues.
Vaidya J, Tobias J, Baum M, Keshtgar M, Houghton J, Wenz F, Corica T, Joseph D.
Lancet Oncol 2004;5(6):339-40
 
Intraoperative radiotherapy for breast cancer.
Vaidya JS, Tobias JS, Baum M, Keshtgar M, Joseph D, Wenz F, Houghton J, Saunders C, Corica T, D'Souza D, Sainsbury R, Massarut S, Taylor I, Hilaris B.
Lancet Oncol 2004;5:165-173

Reducing radiotherapy dose in early breast cancer: the concept of conformal intraoperative brachytherapy.
Tobias J, Vaidya J, Keshtgar M, D'Souza D, Baum M.
Br J Radiol 2004;77(916):279-84

A novel mobile device for intraoperative radiotherapy (IORT).
Kraus-Tiefenbacher U, Steil V, Bauer L, Melchert F, Wenz F.
Onkologie 2003;26:596?598

The novel technique of delivering targeted intraoperative radiotherapy (Targit) for early breast cancer.
Vaidya JS, Baum M, Tobias JS, Morgan S, D'Souza D.
Eur J Surg Oncol. 2002 Jun;28(4):447-54

Targeted intra-operative radiotherapy (Targit): An innovative method of treatment for early breast cancer.
Vaidya JS, Baum M, Tobias JS, D'Souza DP, Naidu SV, Morgan S, Metaxas M, Harte KJ, Sliski AP & Thomson E.
Annals of Oncology 12 (8), 2001, pp. 1075-80

Multicentricity and recurrence of breast cancer.
Baum M, Vaidya JS and Mittra I
Lancet; 349:208.  1997


Ipsilateral breast tumor recurrence and survival following lumpectomy and irradiation: Pathological findings from NSABP protocol B-06.
Fisher ER, Anderson S, Redmond C and Fisher B.
Seminal in Surgical Oncology  8, 161-166. 1992

Clinical and biological implications of the Milan Breast conservation trials.
Vaidya JS and Baum M.
European Journal of Cancer 34, 1143-1144.  1998.

Multicentricity of breast cancer: whole organ analysis and clinical implications.
Vaidya JS, Vyas JJ, Chinoy RF, Merchant NH, Sharma OP and Mittra I.
Br J Cancer 74, 820-24.  1996. 

 

 

Interstitial Irradiation of Brain Tumors Using a Miniature Radiosurgery Device: Initial Experience. Cosgrove GR, Hochberg FH, Pardo FS, Valenzuela RF, Chapman P and Zervas NT: Neurosurgery 40, 518-525.  1997Dosimetric Results from a Feasibility Study of a Novel Radiosurgical Source for Irradiation of Intracranial Metastases. Douglas RM, Beatty J, Gall K, Valenzuela RF, Biggs P, Okunieff and Pardo FS:International Journal of Radiation Oncology Biol. Phys.  36, 443-450.  1996

Multicentricity and its influence on conservative breast cancer treatment strategy.Vaidya JS, Vyas JJ, Mittra I, Chinoy RF. Hong Kong International Cancer Congress, Hong Kong, 17-19 Nov 1995. Abstract 44.4.